Abstract:The Yangtze River has a long history and culture. In the new era, it is of great value to innovate and create popular science activities with the theme of "Yangtze River Great Protection" and solidly promote its dissemination. The popular science work of "Yangtze River Great Protection" should adapt to the characteristics of the new era, strengthen the responsibility of the whole society for popularizing science, create high-quality popular science works, cultivate excellent cultural connotations of the Yangtze River, and thus strive to build a science popularization ecology in the new era led by socialization coordination, standardized construction, digital communication, and value guidancescience.